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dc.contributor.advisorBajgar, Adam
dc.contributor.authorKrejčová, Gabriela
dc.date.accessioned2022-03-08T14:24:40Z
dc.date.available2022-03-08T14:24:40Z
dc.date.issued2018
dc.date.submitted2018-04-17
dc.identifier.urihttps://dspace.jcu.cz/handle/123456789/38634
dc.format97 s.
dc.format97 s.
dc.language.isoeng
dc.publisherJihočeská univerzitacze
dc.rightsBez omezení
dc.subjectPolarization of macrophageseng
dc.subjecthemocyteseng
dc.subjectmetabolic switcheng
dc.subjectD. melanogastereng
dc.subjectHIF1eng
dc.subjectS. pneumoniae infectioneng
dc.titleCharacterization of metabolic changes in hemocytes during the immune response in <i>D. melanogaster</i>cze
dc.title.alternativeCharacterization of metabolic changes in hemocytes during the immune response in <i>D. melanogaster</i>eng
dc.typediplomová prácecze
dc.identifier.stag50420
dc.description.abstract-translatedThe aim of this thesis is to characterize metabolic changes in hemocytes during the immune response in D. melanogaster using in vivo markers as well as by measuring gene expression. The impact of the transcription factor HIF1 on the gene expression of glycolytic enzymes and its impact on the systemic metabolism was evaluated. The importance of HIF1 and LDH in the process of fighting against S. pneumoniae infection was tested as well.eng
dc.date.accepted2018-05-25
dc.description.departmentPřírodovědecká fakultacze
dc.thesis.degree-disciplineExperimentální biologie - specializace Buněčná a vývojová biologiecze
dc.thesis.degree-grantorJihočeská univerzita. Přírodovědecká fakultacze
dc.thesis.degree-nameMgr.
dc.thesis.degree-programBiologiecze
dc.description.gradeDokončená práce s úspěšnou obhajoboucze
dc.contributor.refereeBruce, Alena
dc.contributor.refereeJindra, Marek


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