The role of adenosine receptor in self-activation in immune cells

Abstract

Adenosine receptor plays very important role in regulation of immune response. Its signalling may lead to initiation of metabolic switch, which suppresses energy consumption by peripheral tissues (selfish behaviour of immunes system). In this thesis I attempt to test the potential role of adenosine signalling in self-activation of immune cells which could alternatively explain its role in systemic energetic switch in model organism Drosophila melanogaster.