dc.contributor.advisor | Fessl, Tomáš | |
dc.contributor.author | Ďurinová, Eva | |
dc.date.accessioned | 2021-12-08T12:32:59Z | |
dc.date.available | 2021-12-08T12:32:59Z | |
dc.date.issued | 2016 | |
dc.date.submitted | 2016-04-21 | |
dc.identifier.uri | https://dspace.jcu.cz/handle/123456789/33756 | |
dc.description.abstract | The stability of i-motif structure in the promoter of the insulin gene was investigated by circular dichroism and single-molecule fluorescence resonance energy transfer. The main factor studied was the cytosine methylation and its location in the DNA sequence. Also the molecular crowding effect was examined. In addition, i-motif folding kinetics were investigated by the single molecule method. | cze |
dc.format | 64 s. (67 570 znaků) | |
dc.format | 64 s. (67 570 znaků) | |
dc.language.iso | eng | |
dc.publisher | Jihočeská univerzita | cze |
dc.rights | Bez omezení | |
dc.subject | i-motif | cze |
dc.subject | cytosine methylation | cze |
dc.subject | ILPR | cze |
dc.subject | DNA folding | cze |
dc.subject | single-molecule FRET | cze |
dc.title | The impact of DNA methylation on the stability and dynamics of i-motif in the ILPR promoter region | cze |
dc.title.alternative | The impact of DNA methylation on the stability and dynamics of i-motif in the ILPR promoter region | eng |
dc.type | bakalářská práce | cze |
dc.identifier.stag | 43714 | |
dc.date.accepted | 2016-05-23 | |
dc.description.department | Přírodovědecká fakulta | cze |
dc.thesis.degree-discipline | Chemie | cze |
dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
dc.thesis.degree-name | Bc. | |
dc.thesis.degree-program | Chemie | cze |
dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
dc.contributor.referee | Trantírek, Lukáš | |