| dc.contributor.advisor | Ženka, Jan | |
| dc.contributor.author | Glaserová, Simona | |
| dc.date.accessioned | 2021-12-06T14:19:17Z | |
| dc.date.available | 2021-12-06T14:19:17Z | |
| dc.date.issued | 2015 | |
| dc.date.submitted | 2015-04-21 | |
| dc.identifier.uri | https://dspace.jcu.cz/handle/123456789/24771 | |
| dc.description.abstract | Cílem práce byla náhrada LPS v nádorové imunoterapii. Aplikace poly (I:C) se směsí mannan-SMCC + R-848 vede k synergii, výraznější redukci nádorového růstu a ke statisticky významnému prodloužení přežití. Rovněž byl studován význam a mechanismus působení neutrofilů. | cze |
| dc.format | 66 s. | |
| dc.format | 66 s. | |
| dc.language.iso | cze | |
| dc.publisher | Jihočeská univerzita | cze |
| dc.rights | Bez omezení | |
| dc.subject | rakovina | cze |
| dc.subject | imunoterapie | cze |
| dc.subject | náhrada lipopolysacharidu | cze |
| dc.subject | vrozená imunita | cze |
| dc.subject | neutrofily | cze |
| dc.subject | melanom B16-F10 | cze |
| dc.subject | PAMPs | cze |
| dc.subject | cancer | eng |
| dc.subject | immunotherapy | eng |
| dc.subject | replacement of lipopolysaccharide | eng |
| dc.subject | innate immunity | eng |
| dc.subject | neutrophils | eng |
| dc.subject | melanoma B16-F10 | eng |
| dc.subject | PAMPs | eng |
| dc.title | Studium klinicky aplikovatelné nádorové imunoterapie a jejich mechanismů | cze |
| dc.title.alternative | Study of clinically applicable cancer immunotherapy and their mechanisms | eng |
| dc.type | diplomová práce | cze |
| dc.identifier.stag | 35125 | |
| dc.description.abstract-translated | The aim of this thesis was study of replacement of LPS in innate immunity based cancer immunotherapy. Application of poly (I:C) with mixture of mannan-SMCC + R-848.HCl leads to synergy, higher reduction of tumor growth and significant prolongation of survival. The significance and mechanism of action of neutrophils have also been studied within this therapy. | eng |
| dc.date.accepted | 2015-05-28 | |
| dc.description.department | Přírodovědecká fakulta | cze |
| dc.thesis.degree-discipline | Klinická biologie | cze |
| dc.thesis.degree-grantor | Jihočeská univerzita. Přírodovědecká fakulta | cze |
| dc.thesis.degree-name | Mgr. | |
| dc.thesis.degree-program | Biologie | cze |
| dc.description.grade | Dokončená práce s úspěšnou obhajobou | cze |
| dc.contributor.referee | Kopecký, Jan | |
| dc.contributor.referee | Žampach, Pavel | |
